INDICATIONS & USAGE
Baclofen oral solution is indicated for the treatment of spasticity resulting from multiple sclerosis, particularly for the relief of flexor spasms and concomitant pain, clonus, and muscular rigidity.
Baclofen oral solution may also be of some value in patients with spinal cord injuries and other spinal cord diseases.
Limitations of Use
Baclofen oral solution is not indicated in the treatment of skeletal muscle spasm resulting from rheumatic disorders
WARNINGS AND PRECAUTIONS
Adverse Reactions from Abrupt Withdrawal of Baclofen oral solution
Abrupt discontinuation of baclofen, regardless of the cause, has resulted in adverse reactions that include hallucinations, seizures, high fever, altered mental status, exaggerated rebound spasticity, and muscle rigidity, that in rare cases has advanced to rhabdomyolysis, multiple organ-system failure, and death. Therefore, reduce the dosage slowly when baclofen oral solution is discontinued, unless the clinical situation justifies a rapid withdrawal.
Full Prescribing Information: Daily Med
